{"product_id":"cst-87620s","title":"CST,  87620S, ALKBH3 (E6S4R) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying ALKBH3. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, ALKBH3 (E6S4R) Rabbit Monoclonal Antibody (CST #87620) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nALKBH3 (E6S4R) Rabbit Monoclonal Antibody recognizes endogenous levels of total ALKBH3 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val10 of human ALKBH3 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nALKBH3, also known as Prostate Cancer Antigen-1 (PCA-1), is a DNA and RNA demethylase involved in the repair of alkylated DNA. The protein is overexpressed in prostate cancer and has been linked to other cancer types, including non-small cell lung cancer, renal cell carcinoma, and pancreatic carcinoma (1-3). ALKBH3\/PCA-1 is also a potential therapeutic target in prostate cancer (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nABH3; AlkB homolog 3; alkB homolog 3, alpha-ketoglutarate dependent dioxygenase; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); ALKB3; ALKBH3; Alkylated DNA repair protein alkB homolog 3; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC-1; DEPC1; FLJ43614; hABH3; MGC118790; MGC118792; MGC118793; PCA1; Prostate cancer antigen 1; prostate cancer antigen-1\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 35\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799971647657,"sku":"87620S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-87620s","provider":"Iright","version":"1.0","type":"link"}