{"product_id":"cst-88179s","title":"CST,  88179S, Rapid-Act T Cell Activation Kit (Human, Anti-CD3\/CD28)","description":"Assay Kit for studying in the research area.\n\n\u003cb\u003eStorage\u003c\/b\u003e\nStore at 4ºC. All components in this kit are stable for 12 months when kept in the original format and stored at 4ºC. Once reconstituted, store the Anti-human CD3 and Anti-human CD28 at -80ºC. Aliquot to avoid multiple freeze\/thaw cycles.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Functional\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSpecies Reactivity: Human\n\u003cb\u003eBackground\u003c\/b\u003e\nT cells are activated by signaling through ITAM (immunoreceptor tyrosine-based activation motif)-containing CD3 signaling chains that associate with the T cell receptor (1). Co-stimulation through CD28 on T cells provides an additional signal required for effective T cell activation (2). Antibody-based binding and aggregation of CD3 and CD28 proteins simulates the engagement of a T cell with an antigen presenting cell, and results in T cell activation.","brand":"CST","offers":[{"title":"Default Title","offer_id":46800802644137,"sku":"88179S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-88179s","provider":"Iright","version":"1.0","type":"link"}