{"product_id":"cst-88513t","title":"CST,  88513T, IL-33 (E2T5L) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying IL33. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, IL-33 (E2T5L) Rabbit Monoclonal Antibody (CST #88513) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nIL-33 (E2T5L) Rabbit Monoclonal Antibody recognizes endogenous levels of total IL-33 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with human IL-33 recombinant protein and reacts with an epitope surrounding Glu165.\n\u003cb\u003eBackground\u003c\/b\u003e\nIL-33 (Interleukin-33, NF-HEV) is a nuclear cytokine that is part of the IL-1 family (1,2). Originally discovered as the ‘nuclear factor from high endothelial venules,' it is widely expressed by endothelial cells as well as epithelial barrier tissues (1,5). IL-33 is involved in regulating type 2-associated innate immune responses (2,4). It is the ligand for ST2 which, along with IL-1RAcP, forms the IL-33R signaling complex (2,3). IL-33 functions as an alarmin upon cellular damage or stress, and is associated with allergic inflammation and asthma (5,6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC9orf26; DKFZp586H0523; DVS27; DVS27-related protein; IL-1F11; IL-33; IL1F11; IL33; interleukin 33; Interleukin-1 family member 11; Interleukin-33; Interleukin-33 (109-270); Interleukin-33 (95-270); Interleukin-33 (99-270); NF-HEV; NFEHEV; NFHEV; nuclear factor for high endothelial venules; Nuclear factor from high endothelial venules; RP11-575C20.2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 30\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799982100649,"sku":"88513T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-88513t","provider":"Iright","version":"1.0","type":"link"}