{"product_id":"cst-90520s","title":"CST,  90520S, Glut2 (F6X2X) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Glut2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Glut2 (F6X2X) Rabbit Monoclonal Antibody (CST #90520) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nGlut2 (F6X2X) Rabbit Monoclonal Antibody recognizes endogenous levels of total Glut2 protein. This antibody does not cross-react with Glut1, Glut3, Glut4, or Glut5 protein. This antibody detects a 35 kDa and a 160 kDa protein of unknown identity in some cell lines.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Glut2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nGlucose transporter 2 (Glut2), also known as SLC2A2, is a facilitated hexose transporter. It transports glucose, fructose, and galactose (1-3). Glut2 is expressed in various tissues, such as liver, small intestine, kidney, pancreatic β cells, and central nervous system (1,4). In addition, Glut2 is a marker of mature pancreatic β cells and is required for glucose-stimulated insulin secretion there (1,5). Furthermore, a mutation on human Glut2 protein expressed in oocytes where Val197 is changed to isoleucine was shown to abolish its transport activity (6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nGlucose transporter type 2, liver; GLUT-2; GLUT2; GTR2; SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2; solute carrier family 2 member 2; Solute carrier family 2, facilitated glucose transporter member 2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 50-80\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799999336617,"sku":"90520S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-90520s","provider":"Iright","version":"1.0","type":"link"}