{"product_id":"cst-90694t","title":"CST,  90694T, CD64\/Fc gammaRI (E2O4L) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying FcGR1A mouse. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CD64\/Fc gammaRI (E2O4L) Rabbit Monoclonal Antibody (CST #90694) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD64\/Fc gammaRI (E2O4L) Rabbit Monoclonal Antibody recognizes endogenous levels of total CD64\/FcγRI protein. This antibody does not cross-react with mouse FcγRIV, FcγRIIA, or FcγRIIB.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile256 of mouse CD64\/FcγRI protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD64\/FcγRI (high affinity IgG Fc gamma RI) is an activating Fcγ receptor in the immunoglobulin superfamily, predominantly found on macrophages and monocytes (1-4). CD64 has a high affinity for the antibody-constant region of IgG, with three extracellular Ig-like domains (3). After binding IgG, CD64 interacts with an accessory chain known as the FcR common γ chain (FcRγ), which possesses an immunoreceptor tyrosine-based activation motif (ITAM) that is necessary for triggering cellular activation (2,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAI323638; AV092959; CD64; Fc receptor, IgG, high affinity I; Fc-gamma RI; Fcg1; Fcgam; FcgammaRI; Fcgr1; FCGR1A; FcRI; High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; IgG high affinity Fc receptor; IGGHAFC\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 60-80\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800148267177,"sku":"90694T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-90694t","provider":"Iright","version":"1.0","type":"link"}