{"product_id":"cst-90879s","title":"CST,  90879S, RalB (D9K6M) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying RalB. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, RalB (D9K6M) Rabbit Monoclonal Antibody (CST #90879) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nRalB (D9K6M) Rabbit Monoclonal Antibody recognizes endogenous levels of total RalB protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu142 of human RalB protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nRalA and RalB are members of the Ras family of small GTPases and are highly homologous in protein sequence. The functions of RalA and RalB are distinct yet overlapping. By binding to various effector proteins, RalA and RalB serve as important GTP sensors for exocytosis and membrane trafficking (1-3). RalA is required for Ras-related tumorigenesis (4) and RalB is important for tumor survival (5). In addition to tumor formation, Ral proteins also play a role in cancer cell migration and metastatic tumor invasion (6,7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nGTP binding protein; GTP binding protein); RALB; RALB Ras like proto-oncogene B; RAS like proto-oncogene B; ras related GTP binding protein B; RAS-like protein B; Ras-related protein Ral-B; v-ral simian leukemia viral oncogene homolog B (ras related\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 26\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800001859753,"sku":"90879S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-90879s","provider":"Iright","version":"1.0","type":"link"}