{"product_id":"cst-90916s","title":"CST,  90916S, CD1A (MTB1) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying CD1A. Validated for IHC Leica Bond,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, CD1A (MTB1) Mouse Monoclonal Antibody (CST #90916) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nIHC Leica Bond: 1:50\nImmunohistochemistry (Paraffin): 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody. Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: IHC Leica Bond, Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCD1A (MTB1) Mouse Monoclonal Antibody recognizes endogenous levels of CD1A protein. Non-specific staining was observed in testis by immunohistochemistry.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to the full external domain of human CD1A protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nCD1A is a type 1 cell surface transmembrane glycoprotein structurally similar to MHC Class 1 that is expressed in association with Î²2-microglobulin (1). CD1A is a member of the CD1 family and has been shown to mediate the presentation of primary lipid and glycolipid antigens to T cell lymphocytes for recognition (1,2). It is expressed by Langerhans' cells, cortical double positive and single positive thymocytes, and by interdigitating dendritic cells (1). CD1A has been shown to identify T cell development (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCD1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T-cell surface antigen T6\/Leu-6; T-cell surface glycoprotein CD1a; T6\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nSource\/Isotype: Mouse IgG1 kappa","brand":"CST","offers":[{"title":"Default Title","offer_id":46800289202345,"sku":"90916S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-90916s","provider":"Iright","version":"1.0","type":"link"}