{"product_id":"cst-91974s","title":"CST,  91974S, Human IL-9 Recombinant Protein","description":"Growth Factors and Cytokines for studying IL9 human in the research area.\n\n\u003cb\u003eStorage\u003c\/b\u003e\nHuman IL-9 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg\/ml which can be further diluted in aqueous solutions as needed. Addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage. Once in solution, store at 4°C and use within 1 month, or store at -20ºC to -80ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze\/thaw cycles if storing reconstituted material at -20ºC to -80ºC.\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nRecombinant human IL-9 was expressed in and is supplied in a lyophilized form.\n\u003cb\u003eBackground\u003c\/b\u003e\nInterleukin-9 (IL-9) is a pleiotropic cytokine best known as a T cell and mast cell growth factor (1,2). This T cell stimulator is a member of the common γ-chain-receptor cytokine family; other members include IL-2, IL-4, IL-7, IL-15, and IL-21 (1). IL-9 was first associated with the T helper 2 (T 2) phenotype but is expressed by multiple other T cell subsets, including T 9 cells, T 17 cells, and regulatory T (T ) cells (1-3). The effects of IL-9 are mediated through a heterotypic receptor complex consisting of IL-9 receptor alpha (IL-9Rα) and the common γ-chain (3,4). Binding of IL-9 initiates signaling cascades that involve the cross-phosphorylation of Jak1 and Jak3, leading to the activation of Stat1, Stat3, and Stat5 (1-3).","brand":"CST","offers":[{"title":"Default Title","offer_id":46800717938857,"sku":"91974S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-91974s","provider":"Iright","version":"1.0","type":"link"}