{"product_id":"cst-93122v1","title":"CST,  93122V1, PathScanÂ® RP Phospho-NPM1 (Thr199) Sandwich ELISA Kit","description":"ELISA Kit for studying NPM1 (Thr199) phosphate in the research area.\n\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: ELISA+\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nThe PathScan\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eBackground\u003c\/b\u003e\nNucleophosmin (NPM1), also known as B23, numatrin, or NO38, is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic\/nuclear trafficking, regulation of DNA polymerase Î± activity, centrosome duplication, and molecular chaperoning activities (1,2). The gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM1 portion contributes to transformation by providing a dimerization domain, which activates the fused kinase (3,4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nB23; MGC104254; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin 1; nucleophosmin\/nucleoplasmin family, member 1; Numatrin; testicular tissue protein Li 128\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk","brand":"CST","offers":[{"title":"Default Title","offer_id":46800685269161,"sku":"93122V1","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-93122v1","provider":"Iright","version":"1.0","type":"link"}