{"product_id":"cst-94103s","title":"CST,  94103S, ZBTB32 (F5O1L) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying ZBTB32 mouse. Validated for Western Blotting,Flow Cytometry (Fixed\/Permeabilized). Available in 2 sizes. Highly specific and rigorously validated in-house, ZBTB32 (F5O1L) Rabbit Monoclonal Antibody (CST #94103) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nFlow Cytometry (Fixed\/Permeabilized): 1:100 - 1:400\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Flow Cytometry (Fixed\/Permeabilized)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nZBTB32 (F5O1L) Rabbit Monoclonal Antibody recognizes endogenous levels of total ZBTB32 protein.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of mouse ZBTB32 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nZinc finger and BTB domain-containing 32 (ZBTB32), also known as testis zinc finger protein (TZFP) and repressor of GATA3 (ROG), is a transcription factor that belongs to the BTB\/POZ-ZF protein family and was first identified in immune cell development and tumorigenesis (1,2). These transcription factor family members contain an N-terminal BTB\/POZ domain, which mediates dimerization, and a C-terminal domain with a variable number of zinc fingers that bind DNA (3). ZBTB32 plays a role in T cell homeostasis and inhibits the development of Th2 cells by repressing GATA3 (4,5), and is required for the regulation of CD8 T cells in response to viral infection (6). ZBTB32 is highly expressed by a subset of human and mouse memory B cells but not by naïve B cells (7,8), and is essential for the proliferative burst of natural killer (NK) cells (9).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n4930524C15Rik; FAXF; FAZF; GATA repressor; OTTMUSP00000026619; PLZP; Repressor of GATA; Rog; Testis zinc finger protein; Tzf; Tzfp; ZBT32; Zbtb32; zinc finger and BTB domain containing 32; Zinc finger and BTB domain-containing protein 32\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 50\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800158458025,"sku":"94103S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-94103s","provider":"Iright","version":"1.0","type":"link"}