{"product_id":"cst-96280s","title":"CST,  96280S, BCL7A Antibody","description":"Polyclonal Antibody for studying Bcl-7A. Validated for Western Blotting. Highly specific and rigorously validated in-house, BCL7A Antibody (CST #96280) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nBCL7A Antibody recognizes endogenous levels of total BCL7A protein. This antibody does not cross-react with other BCL7 proteins.\nSpecies Reactivity: Human, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val168 of human BCL7A protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nThe BCL7 family of proteins consisting of BCL7A, BCL7B, and BCL7C are part of the mammalian SWI\/SNF complex (1,2). The BCL7 family has tumor suppressive properties, and differential expression is correlated with poor prognosis of multiple cancer types (2-6). BCL7A was first identified as gene invoked in a MYC-BCL7A fusion in high-grade B-cell non-Hodgkin lymphoma (7). BCL7A also contributes to the function of Purkinje cells (8). BCL7B is deleted in Williams-Beuren syndrome and has been found to play a role in Wnt signaling (9,10).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nB-cell CLL\/lymphoma 7 protein family member A; B-cell CLL\/lymphoma 7A; B-cell CLL\/lymphoma-7; BAF chromatin remodeling complex subunit BCL7A; BCL tumor suppressor 7A; Bcl-7A; BCL7; BCL7A; BCL7A, BAF complex component\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H Mk\nSENSITIVITY: Endogenous\nMW (kDa): 55\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46800053698729,"sku":"96280S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-96280s","provider":"Iright","version":"1.0","type":"link"}