{"product_id":"cst-96857s","title":"CST,  96857S, MT-ATP8 (E2W1A) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MT-ATP8. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, MT-ATP8 (E2W1A) Rabbit Monoclonal Antibody (CST #96857) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMT-ATP8 (E2W1A) Rabbit Monoclonal Antibody recognizes endogenous levels of total MT-ATP8 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro65 of human MT-ATP8 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMitochondrially-encoded ATP Synthase Membrane Subunit 8 (MT-ATP8) is a product of , one of 13 protein-encoding genes in the human mitochondrial genome (1). MT-ATP8 comprises one subunit (ATP synthase F subunit 8) of mitochondrial ATP synthase (Complex V), the inner mitochondrial enzyme that catalyzes the final step of oxidative phosphorylation in the electron transport chain (2). Numerous mutations in  have been identified that have deleterious effects on ATP synthase function, some of which manifest as debilitating neuronal and\/or neuromuscular diseases, including epilepsy, schizophrenia, autism, ataxia, and various cardiomyopathies (3), underscoring the importance of healthy mitochondrial function to organismal health.\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nA6L; ATP synthase F0 subunit 8; ATP synthase protein 8; ATP8; ATPASE8; F-ATPase subunit 8; mitochondrially encoded ATP synthase 8; MT-ATP8; MTATP8\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 9\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800058122409,"sku":"96857S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-96857s","provider":"Iright","version":"1.0","type":"link"}