{"product_id":"cst-96905t","title":"CST,  96905T, MZB1 (E8V4N) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MEDA-7. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, MZB1 (E8V4N) Rabbit Monoclonal Antibody (CST #96905) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMZB1 (E8V4N) Rabbit Monoclonal Antibody recognizes endogenous levels of total MZB1 protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu113 of human MZB1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMarginal zone B- and B1-cell-specific protein (MZB1) is an ER-resident chaperone protein that is expressed by marginal zone B cells and during plasma cell differentiation (1,2). MZB1 possesses oxidoreductase activity that assists in the proper folding, assembly, and secretion of mature IgM by plasma cells (1,3). Research studies have demonstrated that loss of MZB1 expression compromises antibody secretion and humoral immune responses (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\ncaspase-2 binding protein; FLJ32987; HSPC190; marginal zone B and B1 cell specific protein; Marginal zone B- and B1-cell-specific protein; MEDA-7; MEDA7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; MZB1; PACAP; pERp1; plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 20\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800058581161,"sku":"96905T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-96905t","provider":"Iright","version":"1.0","type":"link"}