{"product_id":"cst-99235s","title":"CST,  99235S, NDUFB9 (E7W6K) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying NDUFB9. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, NDUFB9 (E7W6K) Rabbit Monoclonal Antibody (CST #99235) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNDUFB9 (E7W6K) Rabbit Monoclonal Antibody recognizes endogenous levels of total NDUFB9 protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human NDUFB9 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNDUFB9 is an accessory subunit in complex I (NADH: ubiquinone oxidoreductase) of the respiratory chain in mitochondria (1). It is shown that a mutation in the gene leads to reduced NDUFB9 protein levels and lower complex I activity, indicating a role of this mutation in mitochondrial complex I deficiency (2). In addition, research studies using affinity purification and mass spectrometry show that ORF9c of SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) interacts with NDUFB9 in HEK-293T\/17 cells when ORF9c is expressed in HEK-293T\/17 cells (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nB22; CI-B22; complex I B22 subunit; Complex I-B22; DKFZp566O173; FLJ22885; LYR motif-containing protein 3; LYRM3; MC1DN24; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; NADH-ubiquinone oxidoreductase B22 subunit; NADH:ubiquinone oxidoreductase subunit B9; NDUB9; NDUFB9; UQOR22\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 22\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46801041391785,"sku":"99235S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-99235s","provider":"Iright","version":"1.0","type":"link"}