{"product_id":"cst-99258t","title":"CST,  99258T, UQCRC2 (F8Y5N) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying UQCRC2. Validated for Western Blotting,Simple Western™,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, UQCRC2 (F8Y5N) Rabbit Monoclonal Antibody (CST #99258) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nSimple Western™: 1:50 - 1:250\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nUQCRC2 (F8Y5N) Rabbit Monoclonal Antibody recognizes endogenous levels of total UQCRC2 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human UQCRC2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nUbiquinol-cytochrome c reductase complex core protein 2 (UQCRC2), also known as cytochrome b-c1 complex subunit 2, is a component of the ubiquinol-cytochrome c oxidoreductase complex (Complex III) in the mitochondrial electron transport chain (1,2). Studies show that AMPK increases UQCRC2 expression to promote mitophagy, protecting the liver against alcohol-induced injury (3). In addition, overexpression of UQCRC2 was shown to inhibit gastric cancer cell proliferation, invasion, and migration (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nComplex III subunit 2; Core protein II; Cytochrome b-c1 complex subunit 2, mitochondrial; cytochrome bc-1 complex core protein II; MC3DN5; QCR2; ubiquinol-cytochrome c reductase core protein 2; ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2; UQCR2; UQCRC2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 48\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46801041555625,"sku":"99258T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-99258t","provider":"Iright","version":"1.0","type":"link"}