{"product_id":"proteintech-10127-2-ap","title":"Proteintech, 10127-2-AP, PCDHA2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PCDHA2 (10127-2-AP) by Proteintech is a Polyclonal antibody targeting PCDHA2 in WB, IP, ELISA applications with reactivity to human, mouse, rat samples\n10127-2-AP targets PCDHA2 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, Raji cells,  human heart tissue,  HeLa cells,  human brain tissue,  mouse cerebellum tissue,  rat brain tissue,  rat cerebellum tissue\nPositive IP detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProtocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHA2 (protocadherin alpha 2) is a single-pass type I membrane protein containing 6 cadherin domains. It may be involved in the establishment and maintenance of specific neuronal connections in the brain. Three isoforms produced by alternative splicing have been described (UniProt).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag0173 Product name: Recombinant human PCDHA2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 98-259 aa of BC003126 Sequence: RSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGT Predict reactive species\nFull Name: protocadherin alpha 2\nCalculated Molecular Weight: 102 kDa\nObserved Molecular Weight: 102 kDa, 80 kDa\nGenBank Accession Number: BC003126\nGene Symbol: PCDHA2\nGene ID (NCBI): 56146\nRRID: AB_2158964\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9Y5H9\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869725085865,"sku":"10127-2-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-10127-2-ap","provider":"Iright","version":"1.0","type":"link"}