{"product_id":"proteintech-11658-1-ap","title":"Proteintech, 11658-1-AP, CPI17 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CPI17 (11658-1-AP) by Proteintech is a Polyclonal antibody targeting CPI17 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human samples\n11658-1-AP targets CPI17 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MCF-7 cells, HeLa cells,  HepG2 cells,  human colon tissue,  Jurkat cells,  PC-3 cells\nPositive IHC detected in: human stomach cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:400-1:1600\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPPP1R14A, also named as CPI17, belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. CPI17 has two isoforms:CPI-17alpha (17 kDa) and CPI-17beta (13 kDa).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2237 Product name: Recombinant human PPP1R14A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-147 aa of BC021089 Sequence: MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGMEADMPDEINIDELLELESEEERSRKIQGLLKSCGKPVEDFIQELLAKLQGLHRQPGLRQPSPSHDGSLSPLQDRARTAHP Predict reactive species\nFull Name: protein phosphatase 1, regulatory (inhibitor) subunit 14A\nCalculated Molecular Weight: 147 aa, 17 kDa\nObserved Molecular Weight: 17 kDa\nGenBank Accession Number: BC021089\nGene Symbol: CPI17\nGene ID (NCBI): 94274\nRRID: AB_2252794\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96A00\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46886838403241,"sku":"11658-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-11658-1-ap","provider":"Iright","version":"1.0","type":"link"}