{"product_id":"proteintech-12234-1-ap","title":"Proteintech, 12234-1-AP, RAB38 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe RAB38 (12234-1-AP) by Proteintech is a Polyclonal antibody targeting RAB38 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n12234-1-AP targets RAB38 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A375 cells, NIH\/3T3 cells,  HaCaT cells,  MCF-10A cells\nPositive IHC detected in: human gliomas tissue, human lung tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRAB38 (also known as rrGTPbp or NY-MEL-1) is a member of the Rab small GTPase family, which regulates intracellular vesicle trafficking and membrane transport. RAB38 is specifically expressed in lysosome-related organelle (LRO)-containing tissues and cells, such as melanocytes and platelets, where it interacts with its paralogue RAB32 to regulate melanosome biogenesis and transport melanogenic enzymes (e.g., tyrosinase, TRP1, and TRP2) from early\/recycling endosomes to maturing melanosomes.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2874 Product name: Recombinant human RAB38 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-211 aa of BC015808 Sequence: MQAPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDLMESIEPDVVKPHLTSTKVASCSGCAKS Predict reactive species\nFull Name: RAB38, member RAS oncogene family\nCalculated Molecular Weight: 211 aa, 24 kDa\nObserved Molecular Weight: 24 kDa\nGenBank Accession Number: BC015808\nGene Symbol: RAB38\nGene ID (NCBI): 23682\nRRID: AB_2877839\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P57729\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869579497641,"sku":"12234-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-12234-1-ap","provider":"Iright","version":"1.0","type":"link"}