{"product_id":"proteintech-15667-1-ap","title":"Proteintech, 15667-1-AP, DUSP12 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DUSP12 (15667-1-AP) by Proteintech is a Polyclonal antibody targeting DUSP12 in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n15667-1-AP targets DUSP12 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\nPositive IHC detected in: mouse brain tissue, mouse embryo tissue,  mouse kidney tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDUSP12 (Dual specificity protein phosphatase 12) belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. DUSP12 is a kind of dual specificity phosphatase. It can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues and can dephosphorylate glucokinase in vitro (PMID:10446167). In addition, DUSP12 has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates (PMID:24531476). DUSP12 is ubiquitously expressed in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag8131 Product name: Recombinant human DUSP12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-340 aa of BC006286 Sequence: MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI Predict reactive species\nFull Name: dual specificity phosphatase 12\nCalculated Molecular Weight: 370 aa, 43 kDa\nObserved Molecular Weight: 35 kDa\nGenBank Accession Number: BC006286\nGene Symbol: DUSP12\nGene ID (NCBI): 11266\nRRID: AB_3085468\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9UNI6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887350239401,"sku":"15667-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-15667-1-ap","provider":"Iright","version":"1.0","type":"link"}