{"product_id":"proteintech-16901-1-ap","title":"Proteintech, 16901-1-AP, SEC11C Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SEC11C (16901-1-AP) by Proteintech is a Polyclonal antibody targeting SEC11C in WB, ELISA applications with reactivity to human, mouse, rat samples\n16901-1-AP targets SEC11C in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse kidney tissue,  rat kidney tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSEC11C (Signal peptidase complex catalytic subunit SEC11C), also known as SPC21. It is located in the Endoplasmic reticulum membrane. Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum 1. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids. The molecular weight of SEC11C is 22 kDa. It has been reported that its molecular weight is 16kDa (PMID: 38183983).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag10442 Product name: Recombinant human SEC11C protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-192 aa of BC009703 Sequence: MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES Predict reactive species\nFull Name: SEC11 homolog C (S. cerevisiae)\nCalculated Molecular Weight: 192 aa, 22 kDa\nObserved Molecular Weight: 16-22 kDa\nGenBank Accession Number: BC009703\nGene Symbol: SEC11C\nGene ID (NCBI): 90701\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9BY50\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887795196073,"sku":"16901-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-16901-1-ap","provider":"Iright","version":"1.0","type":"link"}