{"product_id":"proteintech-17117-1-ap","title":"Proteintech, 17117-1-AP, KLHL11 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KLHL11 (17117-1-AP) by Proteintech is a Polyclonal antibody targeting KLHL11 in WB, ELISA applications with reactivity to human samples\n17117-1-AP targets KLHL11 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: COLO 320 cells,  MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKLHL11 is a component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating ubiquitination of target proteins. The presence of antibodies directed against KLHL11 has been identified as biomarker of a paraneoplastic neurological syndrome. The downregulation of KLHL11 may contribute to the disease progression, owing to its putative function in protein quality control. The calculated molecular weight of KLHL11 is 80 kDa (PMID: 34312900).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag10805 Product name: Recombinant human KLHL11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 359-708 aa of BC034470 Sequence: DVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYCLENEEAVRKIASQVSDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC Predict reactive species\nFull Name: kelch-like 11 (Drosophila)\nCalculated Molecular Weight: 708 aa, 80 kDa\nObserved Molecular Weight: 80 kDa\nGenBank Accession Number: BC034470\nGene Symbol: KLHL11\nGene ID (NCBI): 55175\nRRID: AB_2130733\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9NVR0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887697809577,"sku":"17117-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-17117-1-ap","provider":"Iright","version":"1.0","type":"link"}