{"product_id":"proteintech-21496-1-ap","title":"Proteintech, 21496-1-AP, SLITRK5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SLITRK5 (21496-1-AP) by Proteintech is a Polyclonal antibody targeting SLITRK5 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n21496-1-AP targets SLITRK5 in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293 cells\nPositive IF\/ICC detected in: A431 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSLITRK5 (NTRK-like protein-5), a neuron-specific transmembrane protein, acts as a negative regulator of hedgehog signaling in osteoblasts. SLITRK5 is selectively expressed in osteoblasts and loss of SLITRK5 enhanced osteoblast differentiation in vitro and in vivo. It is a therapeutic target to enhance bone formation (PMID: 34326333). SLITRK5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice (PMID: 20418887).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag15880 Product name: Recombinant human SLITRK5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 754-935 aa of BC098106 Sequence: HPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQQPPPPPQQPQQQPPPQLQLQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGNSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLEL Predict reactive species\nFull Name: SLIT and NTRK-like family, member 5\nCalculated Molecular Weight: 958 aa, 107 kDa\nObserved Molecular Weight: 100-110 kDa\nGenBank Accession Number: BC098106\nGene Symbol: SLITRK5\nGene ID (NCBI): 26050\nRRID: AB_3085658\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O94991\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869767618729,"sku":"21496-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-21496-1-ap","provider":"Iright","version":"1.0","type":"link"}