{"product_id":"proteintech-21531-1-ap","title":"Proteintech, 21531-1-AP, GUCA1C Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GUCA1C (21531-1-AP) by Proteintech is a Polyclonal antibody targeting GUCA1C in IHC, ELISA applications with reactivity to human, rat samples\n21531-1-AP targets GUCA1C in IHC, ELISA applications and shows reactivity with human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: rat eye tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:400-1:1600\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe guanylate cyclase-activating proteins (GCAPs), Ca2+-binding proteins of the calmodulin gene superfamily, function as regulators of photoreceptor guanylate cyclases (PMID: 15336959). Three different GCAPs (GCAP1, GCAP2, and GCAP3) are identified in vertebrate retina (PMID: 12596930). The cone-specific guanylate cyclase-activating protein 3 (GCAP3) has been shown to regulate the enzymatic activity of membrane-bound guanylate cyclases (GCs) in bovine and teleost fish photoreceptors, to an extent comparable to that of the paralog protein GCAP1 (PMID: 35328663).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag16157 Product name: Recombinant human GUCA1C protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-209 aa of BC103993 Sequence: MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFIDFLEFIAAVNLIVQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK Predict reactive species\nFull Name: guanylate cyclase activator 1C\nCalculated Molecular Weight: 209 aa, 24 kDa\nGenBank Accession Number: BC103993\nGene Symbol: GUCA1C\nGene ID (NCBI): 9626\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O95843\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887662125225,"sku":"21531-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-21531-1-ap","provider":"Iright","version":"1.0","type":"link"}