{"product_id":"proteintech-22697-1-ap","title":"Proteintech, 22697-1-AP, DOK7 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DOK7 (22697-1-AP) by Proteintech is a Polyclonal antibody targeting DOK7 in WB, IHC, ELISA applications with reactivity to human samples\n22697-1-AP targets DOK7 in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, MCF-7 cells,  HEK-293 cells\nPositive IHC detected in: human skeletal muscle tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDOK7, also named as C4orf25, is a MuSK-interacting cytoplasmic protein. DOK7 is essential for neuromuscular synaptogenesis through its interaction with MuSK. It plays an essential role in neuromuscular synaptogenesis. DOK7 acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. DOK7 has some isoforms with MW 53 kDa, 37 kDa, 28 kDa and 64 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag18543 Product name: Recombinant human DOK7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 136-504 aa of BC131544 Sequence: DVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQDSEATLPGPAPGEPWEAGGPHAGPPPAFFSACPVCGGLKVNPPP Predict reactive species\nFull Name: docking protein 7\nCalculated Molecular Weight: 504 aa, 53 kDa\nObserved Molecular Weight: 64 kDa\nGenBank Accession Number: BC131544\nGene Symbol: DOK7\nGene ID (NCBI): 285489\nRRID: AB_2879152\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q18PE1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887292895401,"sku":"22697-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-22697-1-ap","provider":"Iright","version":"1.0","type":"link"}