{"product_id":"proteintech-25226-1-ap","title":"Proteintech, 25226-1-AP, TRPA1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TRPA1 (25226-1-AP) by Proteintech is a Polyclonal antibody targeting TRPA1 in WB, ELISA applications with reactivity to human samples\n25226-1-AP targets TRPA1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, U2OS cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTRPA1 (Transient Receptor Potential Ankyrin 1) is a member of the transient receptor potential (TRP) channel family and is a non-selective cation channel. TRPA1 is predominantly expressed in sensory neurons and is involved in a variety of physiological activities, such as stabilizing cellular membrane potentials, maintaining cellular fluid homeostasis, and regulating intercellular signaling. TRPA1 is a multimodal cell membrane receptor that senses different stimuli and upon activation generates action potential signals via osmolality, temperature and inflammatory factors. TRPA1 has been associated with neurogenic inflammation, osteoarthritis, atopic dermatitis, asthma, inflammatory bowel disease, migraine headache, cancer pain, gout and other diseases, and it is a promising target for drug therapy.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag18685 Product name: Recombinant human TRPA1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-350 aa of BC153003 Sequence: MKRSLRKMWRPGEKKEPQGVVYEDVPDDTEDFKESLKVVFEGSAYGLQNFNKQKKLKRCDDMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT Predict reactive species\nFull Name: transient receptor potential cation channel, subfamily A, member 1\nCalculated Molecular Weight: 1119 aa, 128 kDa\nObserved Molecular Weight: 130 kDa\nGenBank Accession Number: BC153003\nGene Symbol: TRPA1\nGene ID (NCBI): 8989\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O75762\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887840088233,"sku":"25226-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-25226-1-ap","provider":"Iright","version":"1.0","type":"link"}