{"product_id":"proteintech-25713-1-ap","title":"Proteintech, 25713-1-AP, TTC7B Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TTC7B (25713-1-AP) by Proteintech is a Polyclonal antibody targeting TTC7B in WB, IHC, IP, ELISA applications with reactivity to human, mouse samples\n25713-1-AP targets TTC7B in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue\nPositive IP detected in: K-562 cells\nPositive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTTC7B (Tetratricopeptide Repeat Domain 7B) is a protein-coding gene belonging to the tetratricopeptide repeat (TPR) family, which plays critical roles in cellular signaling, membrane dynamics, and disease pathogenesis. TTC7B is associated with focal adhesion (FA) disassembly and cell migration, promoting tumor invasion and metastasis. Its expression is tied to FA-related pathways like the PINCH-ILK-PARVIN complex (PMID: 37990988).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag22388 Product name: Recombinant human TTC7B protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 96-318 aa of BC153122 Sequence: LQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAGDIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPCQSPLDDPLRKGANTKTYTLTRRARVYSGENI Predict reactive species\nFull Name: tetratricopeptide repeat domain 7B\nCalculated Molecular Weight: 843 aa, 94 kDa\nObserved Molecular Weight: 50-53 kDa\nGenBank Accession Number: BC153122\nGene Symbol: TTC7B\nGene ID (NCBI): 145567\nRRID: AB_2880205\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q86TV6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887910670505,"sku":"25713-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-25713-1-ap","provider":"Iright","version":"1.0","type":"link"}