{"product_id":"proteintech-27921-1-ap","title":"Proteintech, 27921-1-AP, PI3 Kinase p110 Alpha Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PI3 Kinase p110 Alpha (27921-1-AP) by Proteintech is a Polyclonal antibody targeting PI3 Kinase p110 Alpha in WB, ELISA applications with reactivity to Human, mouse, rat samples\n27921-1-AP targets PI3 Kinase p110 Alpha in WB, CoIP, ELISA applications and shows reactivity with Human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, mouse brain tissue,  NIH\/3T3 cells,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPIK3CA belongs to the PI3\/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag27539 Product name: Recombinant human PIK3CA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 345-550 aa of BC113601 Sequence: NVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDF Predict reactive species\nFull Name: phosphoinositide-3-kinase, catalytic, alpha polypeptide\nCalculated Molecular Weight: 1068 aa, 124 kDa\nObserved Molecular Weight: 110 kDa\nGenBank Accession Number: BC113601\nGene Symbol: PIK3CA\nGene ID (NCBI): 5290\nRRID: AB_2918135\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P42336\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868872069289,"sku":"27921-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-27921-1-ap","provider":"Iright","version":"1.0","type":"link"}