{"product_id":"proteintech-28750-1-ap","title":"Proteintech, 28750-1-AP, PLK4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PLK4 (28750-1-AP) by Proteintech is a Polyclonal antibody targeting PLK4 in IHC, IF\/ICC, ELISA applications with reactivity to Human, Mouse samples\n28750-1-AP targets PLK4 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with Human, Mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human colon cancer tissue, mouse testis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: hTERT-RPE1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPLK4 (Polo-like kinase 4) is also named SAK, STK18 and belongs to the Ser\/Thr protein kinase family. It plays a central role in centriole duplication and is a kinase implicated in tumor development, which is an upstream regulator of canonical biogenesis necessary for centriole formation. It has 3 isoforms produced by alternative splicing.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, Mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag30482 Product name: Recombinant human PLK4 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 235-426 aa of BC036023 Sequence: SIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGHATISTAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQETSNSGRGRVIQDAEERPHSRYLRRAYSSDRSGTSNSQSQAKTYTMERCHSAEMLSVSKRSGGGENEERYSPTDNN Predict reactive species\nFull Name: polo-like kinase 4 (Drosophila)\nCalculated Molecular Weight: 970 aa, 109 kDa\nGenBank Accession Number: BC036023\nGene Symbol: PLK4\nGene ID (NCBI): 10733\nRRID: AB_2881206\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O00444\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869423227049,"sku":"28750-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-28750-1-ap","provider":"Iright","version":"1.0","type":"link"}