{"product_id":"proteintech-29068-1-ap","title":"Proteintech, 29068-1-AP, Phospho-TBC1D1 (Ser707) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-TBC1D1 (Ser707) (29068-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-TBC1D1 (Ser707) in WB, ELISA applications with reactivity to Human samples\n29068-1-AP targets Phospho-TBC1D1 (Ser707) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Calyculin A treated HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:10000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTBC1D1 belong to the family of RabGAPs and its physiological roles in glucose homeostasis and its implication in human diseases have already been characterized in skeletal muscle and adipocytes in a large number of independent studies. TBC1D1 including twophospho-tyrosine-binding (PTB) domains, a calmodulin-binding domain(CBD) and the func-tional GAP domain responsible for catalyzing GTP hydrolysis. TBC1D1 is phosphorylated by AMPK at Ser660 and Thr237, and by AKT at Thr596. The RabGAPs TBC1D1 is important regulators of glucose homeostasis inskeletal muscle and adipose tissue. (PMID: 31627187, PMID: 18477703)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: TBC1 (tre-2\/USP6, BUB2, cdc16) domain family, member 1\nCalculated Molecular Weight: 133 kDa\nObserved Molecular Weight: 150-160 kDa\nGenBank Accession Number: BC050321\nGene Symbol: TBC1D1\nGene ID (NCBI): 23216\nRRID: AB_3085341\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q86TI0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887761576105,"sku":"29068-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-29068-1-ap","provider":"Iright","version":"1.0","type":"link"}