{"product_id":"proteintech-29304-1-ap","title":"Proteintech, 29304-1-AP, PAFAH Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PAFAH (29304-1-AP) by Proteintech is a Polyclonal antibody targeting PAFAH in WB, IHC, ELISA applications with reactivity to Human, mouse, rat samples\n29304-1-AP targets PAFAH in WB, IHC, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: RAW 264.7 cells, mouse liver tissue,  rat liver tissue\nPositive IHC detected in: human prostate cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPlatelet-activating factor acetylhydrolase (PAFAH) Ib consists of homo- or heterodimers of two PLA2 subunits α1 and α2, and a dimer of a third subunit, LIS1. PAFAH Ib was first discovered by its ability to hydrolyze the extracellular signaling lipid, PAF, which plays a role in platelet activation and inflammation. LIS1, the causative agent of the fatal brain disorder Miller-Dieker lissencephaly, functions independently of the α subunits to regulate the activity of cytoplasmic dynein. LIS1 is a highly conserved protein involved in dynein-mediated processes including nuclear and neuronal migration, centrosomal function, and mitotic spindle orientation. (PMID: 20624900, PMID: 23262398)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse, rat\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag30947 Product name: Recombinant human PLA2G7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 175-290 aa of BC038452 Sequence: AAVEHRDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTLSEDQRFR Predict reactive species\nFull Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)\nCalculated Molecular Weight: 50 kDa\nObserved Molecular Weight: 29-30 kDa, 45-55 kDa\nGenBank Accession Number: BC038452\nGene Symbol: PLA2G7\nGene ID (NCBI): 7941\nRRID: AB_2918276\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q13093\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869723447465,"sku":"29304-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-29304-1-ap","provider":"Iright","version":"1.0","type":"link"}