{"product_id":"proteintech-29450-1-ap","title":"Proteintech, 29450-1-AP, BRCA2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe BRCA2 (29450-1-AP) by Proteintech is a Polyclonal antibody targeting BRCA2 in WB, IHC, ELISA applications with reactivity to human samples\n29450-1-AP targets BRCA2 in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  MCF-7 cells\nPositive IHC detected in: human colon cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\nImmunohistochemistry (IHC): IHC : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nBRCA2, also named as FACD and FANCD1, is involved in double-strand break repair and\/or homologous recombination. BRCA2 may participate in S phase checkpoint activation. Defects in BRCA2 are a cause of genetic susceptibility to breast cancer (BC) which also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag31064 Product name: Recombinant human BRCA2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 210-388 aa of NM_000059 Sequence: IVRNEEASETVFPHDTTANVKSYFSNHDESLKKNDRFIASVTDSENTNQREAASHGFGKTSGNSFKVNSCKDHIGKSMPNVLEDEVYETVVDTSEEDSFSLCFSKCRTKNLQKVRTSKTRKKIFHEANADECEKSKNQVKEKYSFVSEVEPNDTDPLDSNVANQKPFESGSDKISKEVV Predict reactive species\nFull Name: breast cancer 2, early onset\nCalculated Molecular Weight: 384 kDa\nObserved Molecular Weight: 384 kDa\nGenBank Accession Number: NM_000059\nGene Symbol: BRCA2\nGene ID (NCBI): 675\nRRID: AB_2918309\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P51587\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868938981545,"sku":"29450-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-29450-1-ap","provider":"Iright","version":"1.0","type":"link"}