{"product_id":"proteintech-30887-1-ap","title":"Proteintech, 30887-1-AP, Phospho-p130Cas \/ BCAR1 (Tyr410) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-p130Cas \/ BCAR1 (Tyr410) (30887-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-p130Cas \/ BCAR1 (Tyr410) in WB, ELISA applications with reactivity to Human samples\n30887-1-AP targets Phospho-p130Cas \/ BCAR1 (Tyr410) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: pervanadate treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\np130Cas, encoded by the breast cancer anti-estrogen resistance 1 (BCAR1) gene, is a scaffold protein that integrates large multi-protein complexes in response to stimuli such as hormones, growth factors, and integrin engagement. Upon environmental signals, Src family members and focal adhesion kinase (FAK) phosphorylate the p130Cas substrate domain (SD). This active p130Cas can recruit adaptor proteins such as Crk and Nck to its phosphorylated SD. (PMID: 34830244)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: breast cancer anti-estrogen resistance 1\nCalculated Molecular Weight: 870 aa, 93 kDa\nObserved Molecular Weight: 130 kDa\nGenBank Accession Number: BC062556\nGene Symbol: BCAR1\nGene ID (NCBI): 9564\nRRID: AB_3669775\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P56945\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887760691369,"sku":"30887-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-30887-1-ap","provider":"Iright","version":"1.0","type":"link"}