{"product_id":"proteintech-31232-1-ap","title":"Proteintech, 31232-1-AP, RTTN Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe RTTN (31232-1-AP) by Proteintech is a Polyclonal antibody targeting RTTN in WB, ELISA applications with reactivity to human samples\n31232-1-AP targets RTTN in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, HeLa cells,  Jurkat cells,  PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRTTN, also known as Rotatin, is an evolutionarily conserved protein that is associated with the centrosome and plays a crucial role in centriole biogenesis. It is found in many organisms and was initially identified in a mutant mouse that exhibited defects in axial rotation and left-right specification. RTTN is required for proper mitotic progression, the maintenance of spindle pole integrity, and correct spindle positioning. Loss of RTTN can lead to mitotic defects, including G2\/M phase arrest and increased aneuploidy cells.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag34960 Product name: Recombinant human RTTN protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1417-1530 aa of NM_173630 Sequence: TVVNILLDQSECSMVRREAAFILQNLLVIPMPTEIIKDYTWQGPCVHDEDSGLSLIGKPALQALLYHCHFYEHLNQMVKHCYLGRCMFDLNFSAFDRNSESNDLNGLDDSFKFW Predict reactive species\nFull Name: rotatin\nCalculated Molecular Weight: 249 kDa\nObserved Molecular Weight: 246 kDa\nGenBank Accession Number: NM_173630\nGene Symbol: RTTN\nGene ID (NCBI): 25914\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q86VV8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887790641321,"sku":"31232-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-31232-1-ap","provider":"Iright","version":"1.0","type":"link"}