{"product_id":"proteintech-31705-1-ap","title":"Proteintech, 31705-1-AP, IKBKAP Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe IKBKAP (31705-1-AP) by Proteintech is a Polyclonal antibody targeting IKBKAP in WB, ELISA applications with reactivity to Human samples\n31705-1-AP targets IKBKAP in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  U-251 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:12000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag35286 Product name: Recombinant human IKBKAP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1131-1332 aa of NM_001318360.1 Sequence: FSRHKKRLLVVRELKEQAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKKHSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLLD Predict reactive species\nFull Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein\nCalculated Molecular Weight: 150kDa，1332aa\nObserved Molecular Weight: 140-150 kDa\nGenBank Accession Number: NM_001318360.1\nGene Symbol: IKBKAP\nGene ID (NCBI): 8518\nRRID: AB_3670089\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: O95163\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887678345385,"sku":"31705-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-31705-1-ap","provider":"Iright","version":"1.0","type":"link"}