{"product_id":"proteintech-31808-1-ap","title":"Proteintech, 31808-1-AP, SPATA18 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SPATA18 (31808-1-AP) by Proteintech is a Polyclonal antibody targeting SPATA18 in WB, IHC, ELISA applications with reactivity to human, mouse samples\n31808-1-AP targets SPATA18 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse testis tissue\nPositive IHC detected in: rat testis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunohistochemistry (IHC): IHC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe modulation of mitophagy after DNA damage is independent of the type of DNA damage stimuli used and the protein spermatogenesis-associated protein 18 (SPATA18) is an important player in this process (PMID: 32453416; 21264221). SPATA18, also known as MIEAP, is a p53 transcriptional target and was previously reported to contribute to mitochondrial quality control by inducing intramitochondrial lysosome-like organelles after mitochondrial damage (PMID: 21264221).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag36227 Product name: Recombinant human SPATA18 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 102-332 aa of BC025396 Sequence: LQDTFDRERHKDPSPRDRDMQQLDSNLNSTRSQCNQVQDDLVETEKNLEESKNRSAISLLAAEEEINQLKKQLKSLQAQEDARHRNTDQRSSENRRSEPWSLEERKREQWNSLKQNADQQDTEAMSDYKKQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRRPSPNRSKLSNVARKAALLSRFSDSYSQARLDAQCLLRRCIDKAETVQ Predict reactive species\nFull Name: spermatogenesis associated 18 homolog (rat)\nCalculated Molecular Weight: 538 aa, 61 kDa\nObserved Molecular Weight: 61 kDa\nGenBank Accession Number: BC025396\nGene Symbol: SPATA18\nGene ID (NCBI): 132671\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q8TC71\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887813644457,"sku":"31808-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-31808-1-ap","provider":"Iright","version":"1.0","type":"link"}