{"product_id":"proteintech-31847-1-ap","title":"Proteintech, 31847-1-AP, CEP104 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CEP104 (31847-1-AP) by Proteintech is a Polyclonal antibody targeting CEP104 in WB, ELISA applications with reactivity to human samples\n31847-1-AP targets CEP104 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  K-562 cells,  MOLT-4 cells,  SK-BR-3 cells,  hTERT-RPE1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKIAA0562, also known as CEP104 (centrosomal protein 104), is a gene encoding a centrosomal protein that is essential for ciliogenesis and the structural integrity of the cilium tip. During ciliogenesis, CEP104 is translocated from the distal tip of the centriole to the elongated cilium tip. CEP104 is expressed in a variety of cell types, including tissues such as testis and kidney. Mutations in its gene are associated with the autosomal recessive disorder Joubert syndrome, which is characterized by distinctive mid-hindbrain and cerebellar malformations, actinic dyskinesia, irregular breathing, developmental delay, and ataxia. In studies, inhibitors of CEP104 such as Cytochalasin D and Vismodegib have been used to investigate their specific role in cellular function.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag35662 Product name: Recombinant human KIAA0562 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-200 aa of NM_014704.3 Sequence: MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDL Predict reactive species\nFull Name: KIAA0562\nCalculated Molecular Weight: 104kDa，925aa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: NM_014704.3\nGene Symbol: KIAA0562\nGene ID (NCBI): 9731\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: O60308\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46886477988009,"sku":"31847-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-31847-1-ap","provider":"Iright","version":"1.0","type":"link"}