{"product_id":"proteintech-32028-1-ap","title":"Proteintech, 32028-1-AP, KIAA0196 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KIAA0196 (32028-1-AP) by Proteintech is a Polyclonal antibody targeting KIAA0196 in WB, ELISA applications with reactivity to human, mouse samples\n32028-1-AP targets KIAA0196 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, Jurkat cells,  MCF-7 cells,  NIH\/3T3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKIAA0196 is a core component of the WASH complex, an actin-regulating complex involved in intracellular trafficking, mitochondrial metabolism, and myelination. It plays a crucial role in maintaining the structural integrity of myofibrils and regulating cardiac function. Recent studies have identified KIAA0196 as a susceptibility gene for abnormal cardiac development. Mutations or reduced expression of KIAA0196 can lead to cardiac defects, such as enlarged hearts and myocardial contractile dysfunction (PMID: 32417190).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag36916 Product name: Recombinant human KIAA0196 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 950-1159 aa of NM_014846.3 Sequence: KVGQMQILRQQIANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGLLTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPRRVAEAHVPNFIFDEFRTVL Predict reactive species\nFull Name: KIAA0196\nCalculated Molecular Weight: 134kDa，1159aa\nObserved Molecular Weight: 120 kDa\nGenBank Accession Number: NM_014846.3\nGene Symbol: KIAA0196\nGene ID (NCBI): 9897\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q12768\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887694631081,"sku":"32028-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-32028-1-ap","provider":"Iright","version":"1.0","type":"link"}