{"product_id":"proteintech-32308-1-ap","title":"Proteintech, 32308-1-AP, NRAMP1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe NRAMP1 (32308-1-AP) by Proteintech is a Polyclonal antibody targeting NRAMP1 in WB, ELISA applications with reactivity to human samples\n32308-1-AP targets NRAMP1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HL-60 cells, Jurkat cells,  THP-1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSLC11A1 also known as NRAMP1, belongs to the SLC11 family of solute carriers, which mediate the transport of divalent metals. NRAMP1 is a divalent metal importer specifically expressed in the membranes of late endosomes\/lysosomes of professional phagocytes.   It plays a crucial role in the defense against intracellular pathogens by depleting essential metal ions from endocytosed microbes, thereby preventing their proliferation(PMID: 24832660, PMID: 39824808).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1\nCalculated Molecular Weight: 432 aa, 48 kDa\nObserved Molecular Weight: 60 kDa\nGenBank Accession Number: BC071165\nGene Symbol: SLC11A1\nGene ID (NCBI): 6556\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: P49279\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887741948073,"sku":"32308-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-32308-1-ap","provider":"Iright","version":"1.0","type":"link"}