{"product_id":"proteintech-32552-1-ap","title":"Proteintech, 32552-1-AP, KREMEN1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KREMEN1 (32552-1-AP) by Proteintech is a Polyclonal antibody targeting KREMEN1 in WB, ELISA applications with reactivity to human samples\n32552-1-AP targets KREMEN1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKremen protein 1 (KREMEN1, also known as KRM1) is a transmembrane protein that is a negative regulator of the Wnt signaling pathway (PMID: 26206087; 18502762). KREMEN1 is one of the alternative functional receptors that play essential roles in ACE2-independent virus entry, providing insight into SARS-CoV-2 tropism and pathogenesis, as well as a community resource and potential therapeutic strategies for further COVID-19 investigations (PMID: 34837059; 34903854).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37569 Product name: Recombinant human KREMEN1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 100-370 aa of BC063787 Sequence: AEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPP Predict reactive species\nFull Name: kringle containing transmembrane protein 1\nCalculated Molecular Weight: 473 aa, 52 kDa\nObserved Molecular Weight: 52 kDa\nGenBank Accession Number: BC063787\nGene Symbol: KREMEN1\nGene ID (NCBI): 83999\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q96MU8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887699579049,"sku":"32552-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-32552-1-ap","provider":"Iright","version":"1.0","type":"link"}