{"product_id":"proteintech-33035-1-ap","title":"Proteintech, 33035-1-AP, ZNF768 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ZNF768 (33035-1-AP) by Proteintech is a Polyclonal antibody targeting ZNF768 in WB, ELISA applications with reactivity to human samples\n33035-1-AP targets ZNF768 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:12000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nZinc finger protein 768 (ZNF768) is a zinc finger protein that is crucial in linking oncogenic RAS signaling to cellular senescence and proliferation control. It is a transcription factor that associates with euchromatin and promoter regions of many genes in a cell type-specific manner. ZNF768 is required for cell growth and survival, and its depletion induces a strong proliferative and pro-apoptotic response in several cell lines in vitro. ZNF768 is also involved in regulating cell cycle effectors and p53 targets, with its overexpression sufficient to bypass RAS-induced senescence in a p53-dependent manner (PMID: 34404770; 35419475).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37794 Product name: Recombinant human ZNF768 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-175 aa of BC013760 Sequence: MRSPEGYLRGNMSENEEEEISQQEGSGDYEVEEIPFGLEPQSPGFEPQSPEFEPQSPRFEPESPGFESRSPGLVPPSPEFAPRSPESDSQSPEFESQSPRYEPQSPGYEPRSPGYEPRSPGYESESSRYESQNTELKTQSPEFEAQSSKFQEGAEMLLNPDEKSPLNISVGVHPL Predict reactive species\nFull Name: zinc finger protein 768\nCalculated Molecular Weight: 60 kDa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: BC013760\nGene Symbol: ZNF768\nGene ID (NCBI): 79724\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9H5H4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887953432745,"sku":"33035-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33035-1-ap","provider":"Iright","version":"1.0","type":"link"}