{"product_id":"proteintech-33045-1-ap","title":"Proteintech, 33045-1-AP, ARMC12 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ARMC12 (33045-1-AP) by Proteintech is a Polyclonal antibody targeting ARMC12 in WB, IP, ELISA applications with reactivity to human, mouse samples\n33045-1-AP targets ARMC12 in WB, IP, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse testis tissue\nPositive IP detected in: mouse testis tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nARMC12 (Armadillo Repeat Containing 12) is a protein localized to the outer mitochondrial membrane and belongs to the protein family containing Armadillo repeat sequences. Its primary function is to act as a positive regulator of mitochondrial fission. Research indicates that ARMC12 interacts with core proteins involved in mitochondrial fission, such as the dynamin-related protein DRP1 and its receptor MFF, facilitating the proper assembly and localization of the mitochondrial fission complex on the mitochondrial surface, thereby precisely regulating the fission process. Mitochondrial fission is crucial for maintaining mitochondrial network homeostasis, energy metabolism, apoptosis, and autophagy. Consequently, dysfunction of ARMC12 is believed to be potentially associated with diseases related to abnormal mitochondrial morphology, such as neurodegenerative diseases, metabolic disorders, and cancer, making it an important subject of study in the field of mitochondrial dynamics.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37979 Product name: Recombinant human C6orf81 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-367 aa of BC033033 Sequence: MGKSIPQYLGQLDIRKSVVSLATGAGAIYLLYKAIKAGIKCKPPLCSNSPICIARECPGPGERALPQEAPAPEASAVGGPKGLAVERERHGRDSGELRRLLNSLECKQDEYAKSMILHSITRCVYLLEAEASACTTDDIVLLGYMLDDKDNSVKTQALNTLKAFSGIRKFRLKIQEHSIKVLELISTIWDTELHIAGLRLLNNLPLPDYVHPQLRRVMPALMEILQSDYILAQVQAVRLLSYLAQKNDLLYDILNCQVHSNFLNLFQPTQSGSLLYEVLVFAERLSEGRNAPHYHVVKWHYNEQSLHESLFGEESRLADRLLALVIHPEEDVQIQACKVIVSLQYPQDLRARPSSCQPSRSYFKNTE Predict reactive species\nFull Name: chromosome 6 open reading frame 81\nObserved Molecular Weight: 37 kDa\nGenBank Accession Number: BC033033\nGene Symbol: C6orf81\nGene ID (NCBI): 221481\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q5T9G4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46885049204905,"sku":"33045-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33045-1-ap","provider":"Iright","version":"1.0","type":"link"}