{"product_id":"proteintech-33151-1-ap","title":"Proteintech, 33151-1-AP, INSM2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe INSM2 (33151-1-AP) by Proteintech is a Polyclonal antibody targeting INSM2 in WB, ELISA applications with reactivity to human samples\n33151-1-AP targets INSM2 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, Calu-1 cells,  SH-SY5Y cells,  SK-N-SH cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nINSM2 (Insulinoma-associated protein 2) is a zinc-finger protein belonging to the transcription factor family and has transcriptional repressive functions. It may exert growth-inhibitory or tumor-suppressive effects in hepatocytes and certain neurons. The primary function of INSM2 involves the regulation of gene expression, particularly the repression of insulin gene expression in non-pancreatic cells.\nAdditionally, INSM2 is upregulated in neuroblastoma and is associated with poor prognosis. It promotes tumor development by affecting lipid metabolism through the regulation of the mTOR signaling pathway.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag38945 Product name: Recombinant human INSM2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-210 aa of NM_032594.3 Sequence: MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASG Predict reactive species\nFull Name: insulinoma-associated 2\nCalculated Molecular Weight: 59kDa，566aa\nObserved Molecular Weight: 68 kDa\nGenBank Accession Number: NM_032594.3\nGene Symbol: INSM2\nGene ID (NCBI): 84684\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q96T92\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887685128361,"sku":"33151-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33151-1-ap","provider":"Iright","version":"1.0","type":"link"}