{"product_id":"proteintech-33159-1-ap","title":"Proteintech, 33159-1-AP, BMP-9 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe BMP-9 (33159-1-AP) by Proteintech is a Polyclonal antibody targeting BMP-9 in WB, ELISA applications with reactivity to mouse, rat samples\n33159-1-AP targets BMP-9 in WB, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse liver tissue, rat liver tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nBone Morphogenetic Protein 9 (BMP9), also known as Growth Differentiation Factor 2 (GDF-2), is a cytokine belonging to the transforming growth factor-β (TGF-β) superfamily. BMP9 is mainly produced by hepatocytes and hepatic stellate cells in the liver and is secreted into the bloodstream, where it acts as a circulating factor involved in various physiological processes. BMP9 is synthesized as a precursor protein (pre-proBMP9) composed of 429 amino acids (aa) that includes a 22 aa signal peptide, a 297 aa prodomain (33 kDa) and a 110 aa mature protein (12.5 kDa). It is then cleaved by serine endoproteases, leading to a short dimeric mature form of 25 kDa, and the prodomain which can remain noncovalently associated with the mature short form, giving a size of about 100 kDa. (PMID:21710321)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Eg2482 Product name: recombinant mouse Gdf2 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 23-428 aa of NM_019506.4 Sequence: KPLQNWEQASPGENAHSSLGLSGAGEEGVFDLQMFLENMKVDFLRSLNLSGIPSQDKTRAEPPQYMIDLYNRYTTDKSSTPASNIVRSFSVEDAISTAATEDFPFQKHILIFNISIPRHEQITRAELRLYVSCQNDVDSTHGLEGSMVVYDVLEDSETWDQATGTKTFLVSQDIRDEGWETLEVSSAVKRWVRADSTTNKNKLEVTVQSHRESCDTLDISVPPGSKNLPFFVVFSNDRSNGTKETRLELKEMIGHEQETMLVKTAKNAYQVAGESQEEEGLDGYTAVGPLLARRKRSTGASSHCQKTSLRVNFEDIGWDSWIIAPKEYDAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISILYKDDMGVPTLKYHYEGMSVAECGCR Predict reactive species\nFull Name: growth differentiation factor 2\nCalculated Molecular Weight: 48 kDa\nObserved Molecular Weight: 33 kDa\nGenBank Accession Number: NM_019506.4\nGene Symbol: BMP9\nGene ID (NCBI): 12165\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9WV56\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46885251285161,"sku":"33159-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33159-1-ap","provider":"Iright","version":"1.0","type":"link"}