{"product_id":"proteintech-33574-1-ap","title":"Proteintech, 33574-1-AP, ESS2\/DGCR14 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ESS2\/DGCR14 (33574-1-AP) by Proteintech is a Polyclonal antibody targeting ESS2\/DGCR14 in WB, ELISA applications with reactivity to human samples\n33574-1-AP targets ESS2\/DGCR14 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: DU 145 cells, HEK-293 cells,  LNCaP cells,  PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:12000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nESS2 splicing factor homolog (ESS2), also named DiGeorge-syndrome critical region 14 (DGCR14), acts as a transcriptional co-activator for retinoic acid receptor-related orphan nuclear receptor gamma\/gamma-t (Rorγ\/γt). Ess2 is a nuclear protein with a coiled-coil domain [6] that is conserved from yeasts to humans. ESS2 is a member of the deletion gene cluster in the 22q11.2 deletion syndrome (22q11.2DS, also known as DiGeorge syndrome or CATCH 22 syndrome). The syndrome is characterized by varying defects of the heart, thymus and parathyroid glands.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37915 Product name: Recombinant human ESS2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-250 aa of NM_022719 Sequence: METPGASASSLLLPAASRPPRKREAGEAGAATSKQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTR Predict reactive species\nFull Name: DiGeorge syndrome critical region gene 14\nCalculated Molecular Weight: 476aa, 53 kDa\nObserved Molecular Weight: 50-60 kDa\nGenBank Accession Number: NM_022719\nGene Symbol: DGCR14\nGene ID (NCBI): 8220\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q96DF8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887628275881,"sku":"33574-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33574-1-ap","provider":"Iright","version":"1.0","type":"link"}