{"product_id":"proteintech-33666-1-ap","title":"Proteintech, 33666-1-AP, CD228\/MFI2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD228\/MFI2 (33666-1-AP) by Proteintech is a Polyclonal antibody targeting CD228\/MFI2 in WB, ELISA applications with reactivity to mouse samples\n33666-1-AP targets CD228\/MFI2 in WB, ELISA applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD228, also known as Melanotransferrin (MTF), p97, MFI2, etc., is an iron-binding glycoprotein belonging to the transferrin family. In normal tissues, the expression of CD228 is low, mainly confined to skin epidermis, brain endothelium, renal tubules, sweat gland and salivary gland ducts. However, in many tumor tissues, such as melanoma, non-small cell lung cancer, colorectal cancer, pancreatic cancer and so on, the expression of CD228 increased significantly. Soluble CD228 can cross the blood-brain barrier by interacting with transferrin receptor. In the brain, CD228 is located in microglia related to amyloid plaque cells in Alzheimer's disease. The increased concentration of CD228 in serum can be regarded as a surrogate marker of Alzheimer's disease.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Eg6302 Product name: Recombinant mouse CD228\/MFI2 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 20-708 aa of NM_013900.2 Sequence: VMEVQWCTISDAEQQKCKDMSEAFQGAGIRPSLLCVQGNSADHCVQLIKEQKADAITLDGGAIYEAGKEHGLKPVVGEVYDQDIGTSYYAVAVVRRNSNVTINTLKGVKSCHTGINRTVGWNVPVGYLVESGHLSVMGCDVLKAVGDYFGGSCVPGTGETSHSESLCRLCRGDSSGHNVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGNTLPSWGKSLMSEDFQLLCRDGSRADITEWRRCHLAKVPAHAVVVRGDMDGGLIFQLLNEGQLLFSHEDSSFQMFSSKAYSQKNLLFKDSTLELVPIATQNYEAWLGQEYLQAMKGLLCDPNRLPHYLRWCVLSAPEIQKCGDMAVAFSRQNLKPEIQCVSAESPEHCMEQIQAGHTDAVTLRGEDIYRAGKVYGLVPAAGELYAEEDRSNSYFVVAVARRDSSYSFTLDELRGKRSCHPYLGSPAGWEVPIGSLIQRGFIRPKDCDVLTAVSQFFNASCVPVNNPKNYPSALCALCVGDEKGRNKCVGSSQERYYGYSGAFRCLVEHAGDVAFVKHTTVFENTNGHNPEPWASHLRWQDYELLCPNGARAEVDQFQACNLAQMPSHAVMVRPDTNIFTVYGLLDKAQDLFGDDHNKNGFQMFDSSKYHSQDLLFKDATVRAVPVREKTTYLDWLGPDYVVALEGMLSQQ Predict reactive species\nFull Name: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5\nCalculated Molecular Weight: 81 kDa\nObserved Molecular Weight: 81 kDa\nGenBank Accession Number: NM_013900.2\nGene Symbol: Mfi2\nGene ID (NCBI): 30060\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9R0R1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46886140805289,"sku":"33666-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33666-1-ap","provider":"Iright","version":"1.0","type":"link"}