{"product_id":"proteintech-33831-1-ap","title":"Proteintech, 33831-1-AP, WDR12 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe WDR12 (33831-1-AP) by Proteintech is a Polyclonal antibody targeting WDR12 in WB, ELISA applications with reactivity to human samples\n33831-1-AP targets WDR12 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nWDR12 is a nucleolar WD-repeat scaffolding protein and an essential component of the PeBoW complex required for 60S ribosomal subunit maturation. By driving pre-rRNA processing, WDR12 supports cell growth and proliferation, while its disruption activates the p53-dependent nucleolar stress pathway. Upregulated in multiple cancers and genetically linked to cardiometabolic traits, WDR12 serves as a central regulator of ribosome biogenesis, cell-cycle control, and cellular homeostasis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag38016 Product name: Recombinant human WDR12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 74-423 aa of BC008082 Sequence: NISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA Predict reactive species\nFull Name: WD repeat domain 12\nCalculated Molecular Weight: 423 aa, 48 kDa\nObserved Molecular Weight: 47 kDa\nGenBank Accession Number: BC008082\nGene Symbol: WDR12\nGene ID (NCBI): 55759\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9GZL7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887922041001,"sku":"33831-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-33831-1-ap","provider":"Iright","version":"1.0","type":"link"}