{"product_id":"proteintech-51004-1-ap","title":"Proteintech, 51004-1-AP, GEFT Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GEFT (51004-1-AP) by Proteintech is a Polyclonal antibody targeting GEFT in WB, ELISA applications with reactivity to human, mouse, rat samples\n51004-1-AP targets GEFT in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissues\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q\/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. GEFT is  expressed  as three isoforms (64, 53 and 68kDa).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: RhoA\/RAC\/CDC42 exchange factor\nCalculated Molecular Weight: 64 kDa\nObserved Molecular Weight: 70 kDa\nGenBank Accession Number: BC047559\nGene Symbol: GEFT\nGene ID (NCBI): 115557\nRRID: AB_2089321\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q86VW2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869462974633,"sku":"51004-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-51004-1-ap","provider":"Iright","version":"1.0","type":"link"}