{"product_id":"proteintech-55182-1-ap","title":"Proteintech, 55182-1-AP, DCTN1\/p150 glued Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DCTN1\/p150 glued (55182-1-AP) by Proteintech is a Polyclonal antibody targeting DCTN1\/p150 glued in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, canine samples\n55182-1-AP targets DCTN1\/p150 glued in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, canine samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human brain tissue, HeLa cells,  Jurkat cells\nPositive IHC detected in: human brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: MDCK cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:20-1:200\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDCTN1, also named as DAP-150, p150-glued and p135, belongs to the dynactin 150 kDa subunit family. It is required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B). This antibody is specific to DCTN1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, canine\nCited Reactivity: human, mussel\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: dynactin 1 (p150, glued homolog, Drosophila)\nCalculated Molecular Weight: 142 kDa\nObserved Molecular Weight: 135 kDa, 150 kDa\nGenBank Accession Number: NM_004082\nGene Symbol: p150 glued\nGene ID (NCBI): 1639\nRRID: AB_10837074\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q14203\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869456158889,"sku":"55182-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-55182-1-ap","provider":"Iright","version":"1.0","type":"link"}