{"product_id":"proteintech-55192-1-ap","title":"Proteintech, 55192-1-AP, CSNK1A1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CSNK1A1 (55192-1-AP) by Proteintech is a Polyclonal antibody targeting CSNK1A1 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, rat samples\n55192-1-AP targets CSNK1A1 in WB, IHC, IF\/ICC, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse brain tissue,  Jurkat cells,  MCF-7 cells,  NIH\/3T3 cells,  U-87 MG cells,  rat brain tissue\nPositive IHC detected in: human breast cancer tissue, human lung cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCSNK1A1, also named as CK1, belongs to the protein kinase superfamily, CK1 Ser\/Thr protein kinase family and Casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. CSNK1A1 phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. This antibody is specific to CSNK1A1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: casein kinase 1, alpha 1\nCalculated Molecular Weight: 42 kDa\nObserved Molecular Weight: 30-35 kDa, 42-45 kDa\nGenBank Accession Number: NM_001892\nGene Symbol: CSNK1A1\nGene ID (NCBI): 1452\nRRID: AB_11183034\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P48729\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868896546985,"sku":"55192-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-55192-1-ap","provider":"Iright","version":"1.0","type":"link"}