{"product_id":"proteintech-55408-1-ap","title":"Proteintech, 55408-1-AP, HIPK2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe HIPK2 (55408-1-AP) by Proteintech is a Polyclonal antibody targeting HIPK2 in WB, IHC, ELISA applications with reactivity to human, mouse, rat samples\n55408-1-AP targets HIPK2 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse kidney tissue\nPositive IHC detected in: mouse brain tissue, human gliomas tissue,  human renal cell carcinoma tissue,  mouse heart tissue,  mouse kidney tissue,  rat brain tissue,  rat heart tissue,  rat kidney tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunohistochemistry (IHC): IHC : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHIPK2 is a serine\/threonine kinase participating in transcriptional regulation, growth control, and apoptosis. The kinase contributes to the regulation of remarkably diverse pathways such as p53 activation or Wnt signaling. There is very low levels of HIPK2 protein expression in several thyroid tumors and the combination of HIPK2 and Gal-3,would be helpful in ameliorating the preoperative recognition of thyroid cancer. HIPK2 may represent a new tumour suppressor gene for these types of cancers and may constitute a new potential promising diagnostic marker and therapeutic target.(PMID:21698151).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: homeodomain interacting protein kinase 2\nCalculated Molecular Weight: 131 kDa\nObserved Molecular Weight: 131 kDa, 101 kDa\nGenBank Accession Number: NM_022740\nGene Symbol: HIPK2\nGene ID (NCBI): 28996\nRRID: AB_2881323\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9H2X6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868934099113,"sku":"55408-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/proteintech-55408-1-ap","provider":"Iright","version":"1.0","type":"link"}